Biomedical Science Letters

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Fig. 3.

The Phospho-Rab10 level was reduced by LRRK2 kinase inhibitor treatment in rat primary astrocytes. The cells were treated with or without lipopolysaccharide (LPS, 1 μg/mL) and GSK2578215A (3 μM) for 24 h. The cell lysates were subjected to SDS-PAGE and analyzed with the indicated antibodies. A. A representative of western blot analysis after indicated treatment. (*nonspecific band; n=3) B. C. Relative densitometric levels of pS935-LRRK2 which were normalized to α-tubulin (B) and pRab10/Rab10 (C). *P<0.05, **P<0.01, ****P<0.0001.

Biomed Sci Letters 2019;25:177-84
© 2019 Biomed Sci Letters