Biomedical Science Letters

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Table. 2.

Replication results of linear regression analyses for RBC indices in Korean population and comparison of Fst for between two population

GeneSNPEAEuropeanKoreanFst


EAFbetaP-valueEAFbetaP-value

Hemoglobin
ATXN2rs10774625A0.4770.06121.44X10-90.0220.02750.6480.277
BRAPrs11065987G0.4190.06711.32X10-80.025-0.01630.7700.224
HIST1H1Ars9393681C0.4560.07176.95X10-110.7850.00060.9770.115
HIST1H1Crs9295685C0.4000.08874.11X10-130.737-0.00750.7040.116
HIST1H1Trs198833G0.1780.09709.48X10-100.0460.01420.7320.043
LRRC16rs17492120T0.1040.09691.65 X 10-80.037-0.00580.8990.017
MPSTrs5750373A0.4140.05812.10X10-80.6840.03620.0510.074
rs8141597C0.3470.06381.47 X 10-80.6590.02670.1440.097
PRKCErs10495928A0.6830.07447.58X10-100.8070.06503.08X10-32.01X10-2
PTPN11rs11066301G0.4270.06301.29 X 10-90.028-0.07090.1800.226
rs9348689T0.5520.08393.80X10-110.659-0.03570.0560.012
rs932316C0.4380.07884.76X10-90.1390.02040.4160.109
SCGNrs1321247T0.1760.12091.12 X 10-90.0340.02840.5500.054
rs2205936C0.5520.06869.15X10-90.730-0.01010.6040.034
rs9467556C0.1470.07939.61X10-90.1330.02670.2963.84X10-4
rs2235321A0.4240.06141.11X10-80.4940.08381.58X10-64.91X10-3
TMPRSS6rs5756505C0.4320.06393.99X10-100.4990.08371.30X10-64.52X10-3
rs855791G0.6120.09441.40X10-150.5060.08004.64X10-61.14X10-2
TRAFD1rs17630235A0.4100.06635.70X10-100.031-0.04560.3700.209
TRIM38rs12216125T0.3590.08101.55X10-110.1210.02150.4210.078
TSHZ2rs6013509G0.7500.06991.96 X 10-90.6610.01870.3089.63X10-3

Hematocrit

ATXN2rs10774625A0.4770.17024.88X10-100.0220.18590.2860.277
BRAPrs11065987G0.4190.18093.34X10-100.0250.13400.4090.224
rs69202110.7360.20966.96X10-110.6530.25691.21X10-68.19X10-3
HBS1Lrs9389268A0.7490.19781.60X10-100.6800.34511.53X10-105.83X10-3
rs9483788T0.7650.21723.55X10-110.6730.22473.38X10-51.04X10-2
PRKCErs10184620A0.9110.28347.23X10-90.9870.32590.1280.029
rs4953318A0.6270.20101.18X10-120.7780.23031.32X10-42.73X10-2
PTPN11rs11066301G0.4270.16473.97X10-90.028-0.10550.4910.226
SCGNrs9348689T0.5520.17821.28X10-80.659-0.13041.62X10-21.19X10-2
TFR2rs7385804C0.3780.15922.75X10-80.1340.01960.7910.078
TMPRSS6rs2413450C0.5810.16206.33X10-90.5000.18582.14X10-46.69X10-3
TRAFD1rs11066188A0.4100.17481.21 X 10-90.0310.04670.7530.209

The replicated SNPs are indicated in bold. Abbreviations: SNP, single nucleotide polymorphism; EA, effect allele; EAF, effect allele frequency; Fst, F-statistics

Biomed Sci Letters 2019;25:190-5 https://doi.org/10.15616/BSL.2019.25.2.190
© 2019 Biomed Sci Letters