Biomedical Science Letters

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Fig. 2.

Induction of apoptotic-related genes by CCN3-R239Q overexpression in Neuro2a cells. Anti-apoptotic (Xnip, Mcl-1, Bcl-2, Bcl2-like 1, and Bcl2-like 2) and pro-apoptotic (Puma, Diablo, Casp2, 3, 6, 7, 9, Bok, Bnip-like, Bim, Bid, Bax, Bak1, Bad, and Apaf) mRNA levels were evaluated by real time qPCR in Neuro2a cells transfected with or without CCN3-R239Q mutants for 24 h. The relative mRNA expression levels were normalized to those of Gapdh. Results are presented as means ± standard deviation of 3 separate experiments.

Biomed Sci Letters 2018;24:64-75
© 2018 Biomed Sci Letters