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Effects of Houttuynia cordata Extracts of Different Aerial Parts on Antioxidants and Anti-inflammatory
Biomed Sci Letters 2018;24:87-93
Published online June 30, 2018;  https://doi.org/10.15616/BSL.2018.24.2.87
© 2018 The Korean Society For Biomedical Laboratory Sciences.

Sung-Gyu Lee and Hyun Kang

Department of Medical Laboratory Science, College of Health Science, Dankook University, Cheonan-si, Chungnam 31116, Korea
Correspondence to: Hyun Kang. Department of Medical Laboratory Science, College of Health Science, Dankook University, Cheonan-si, Chungnam 31116, Korea.
Tel: +82-41-550-3015, Fax: +82-41-559-7934, e-mail: hkang@dankook.ac.kr
Received May 3, 2018; Revised June 22, 2018; Accepted June 25, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
The current study was carried out to determine the effects of the leaf and root of Houttuynia cordata Thunb on antioxidant and anti-inflammatory. Total polyphenol contents of leaf and root ethanol extracts were found to be 59.32 and 12.07 mg/g, respectively. Also, total flavonoid contents of leaf and root ethanol extracts were found to be 10.85 and 8.55 mg/g, respectively. The RC50 values of DPPH radical scavenging of leaf and root ethanol extracts were 23.51 and 154.72 μg/mL, respectively. The RC50 values of ABTS radical scavenging of leaf and root ethanol extracts were 35.42 and 233.89 μg/mL, respectively. The antioxidant activities in leaf ethanol extracts were higher in root. Also, to confirm anti-inflammatory activity of ethanol extract, we treat leaf and root of Houttuynia cordata Thunb extract on BV-2 cell with LPS. The NO inhibition effects in of Houttuynia cordata Thunb leaf ethanol extracts showed higher values compared with the root ethanol extracts. These results indicate that Houttuynia cordata Thunb ethanol extracts may play a positive role in antioxidant and anti-inflammatory.
Keywords : Houttuynia cordata, Leaf, Polyphenol, BV-2, Antioxidant