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Organization of the manuscript

The file of manuscript is saved in the native format of the word processor used. Manuscripts must be typed on 21 횞 29.7 cm (A4 size) paper with at least 30 mm wide margins on all sides. The text must be typed in a font size of at least ten points. The manuscript is to be arranged in the following order: (a) Cover letter; (b) Title page, Author(s), Complete Address(es) of Institution(s), and Abbreviations; (c) Title, Abstract and Keywords; (d) Introduction; (e) Materials and Methods; (f) Results; (g) Discussion; (h) Acknowledgements; (i) References; (j) Figure legends; (k) Tables; and (l) Figures. All pages are numbered with the title page as page 1. The paper should be arranged horizontally and double spaced, with exact spelling and spacing. Reviews, notes and brief communications should be organized in the order of the title, abstract, content, reference, the legend of tables, the legend of figures, and tables and figures.
  • 1) Cover letter:
    A cover letter should include the title of the paper and is used to explain why your paper should be published in this journal rather than elsewhere.
  • 2) Title page:
    The title page should include the title, the name of the author(s), address, a corresponding author's address, and abbreviations. The title in Korean as well as in English should be written and should be easily, rapidly and correctly understood by both the scientific or technical reader (English less than 15 words). Addresses should consist of at least (1) affiliation (department, institution), (2) street with number or postbox number, (3) postal or zip code, (4) town or city, (5) country. The relationship among authors should be indicated by a superscript number. The corresponding author should be indicated by the symbol "". The address of corresponding author including name, telephone, fax and e-mail address should be described. Standard abbreviations may be used without definition. Any nonstandard abbreviations should be spelled out on first use, followed by the abbreviated form in parentheses. Thereafter, abbreviated form may be used throughout the manuscript. Undefined abbreviations cannot be used. Provide a list of all nonstandard abbreviations in alphabetical order on a page following the title page.
  • 3) Title, Abstract and Keywords:
    The abstract should succinctly and clearly describe the major findings reported in the manuscript. It must not exceed 250 words. Key words (4 ~ 10)should be no mo should be provided on the abstract paper with the first letter capitalizedre than 10 words with a capital letter in the beginning. The keywords should be standard MeSH-Medline terms (http://www.nlm.nih.gov/mesh).
  • 4) Main text:
    The main text of the paper should be organized in the order of introduction, materials and methods, results, discussion, acknowledgements. The results and discussion can be described as a whole only when it is acknowledged to be necessary for the content of the paper. In the results section, the international system of Units (SI units) is required.
  • 5) References:
    Authors and years of reference in the contents should be written within parentheses (In case of a single author, they should be written as Jackson, 1985. In case of two authors, they should be written as Kang and Smith, 1999, and in case of three authors or more, they should be written as Steggles et al., 2003). When several papers are quoted at the same time, they should be listed in the order of the publication year (e.g. Kang, 1985; Drakes et al., 2004). The papers of the same author published in the same year should be distinguished by a and b (e.g. smith et al., 2004a; smith et al., 2004b). The papers quoted in the content should be arranged in alphabetic order of authors' family name in the reference of the paper.
    - The way to list referenced sources is as below.

    • (1)Journal: the name of the author, the title of the paper, the name of the journal, the year of publication, the volume number: the beginning page-the ending page (The title of the paper should be written in a lower-case letters except for the first letter).
      • Ex)
      • De Robertis M, Massi E, Poeta ML, Carotti S, Morini S, Cecchetelli L, Signori E, Fazio VM. The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. Journal of Carcinogenesis. 2011. 10: 9.
      • De Sanjose S, Quint WG, Alemany L, Geraets DT, Klaustermeier JE, Lloveras B, Tous S, Felix A, Bravo LE, Shin HR, Vallejos CS, de Ruiz PA, Lima MA, Guimera N, Clavero O, Alejo M, Llombart-Bosch A, Cheng-Yang C, Tatti SA, Kasamatsu E. et al. Human papillomavirus genotype attribution in invasive cervical cancer: A retrospective cross-sectional worldwide study. Lancet Oncology. 2010. 11: 1048-1056.
      • Deng Z, Mu J, Tseng M, Wattenberg B, Zhuang X, Egilmez NK, Wang Q, Zhang L, Norris J, Guo H, Yan J, Haribabu B, Miller D, Zhang HG. Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. Nature Communications. 2015. 6: 6956.
      • Franco AA, Mundy LM, Trucksis M, Wu S, Kaper JB, Sears CL. Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene. Infection and Immunity. 1997. 65: 1007-1013.
      • Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L, Karin M. IL-6 and STAT3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell. 2009. 15: 103-113
    • (2) Book: the name of the author, the name of the book or chapter (the name of the editor), the year of publication, the volume number and the number of pages, the name of the publishing company, the city and country of publication. (The volume number and the number of pages, and the city and country of publication should be separated by a comma, while other items are separated by a period. The volume number and the city of publication may be omitted.)
      • Ex)
      • Smabrook J, Fritsch EF, Maniatis T. Molecular cloning: A laboratory manual. 1989. pp 1339-1341. Cold Spring Harbor Laboratory Press. NY, USA.
      • Messing J. New M13 vectors for cloning in Methods in enzymology (Wu R, Grossman L, Moldave K. Eds). 1983. Vol 101, pp 20-51. Academic Press. NY, USA.
    • (3) During publication: the name of the author, the name of the paper, the name of the journal, the year of publication. (in press)
      • Ex)
      • Choi EG, Yang EJ, Kim D-H, Lee JS, Kim IS. CCR expression of bronchoalveolar lavage fluid (BALF) neutrophils and chemotactic activity of BALF. J Exp Biomed Sci. 2011. (in press)
  • 6) Figure legend, tables and Figures:
    The tables and figures should be organized in the order of legends, tables, and figures, and each table or figure should be arranged on a separate page. Tables should have titles and sufficient experimental detail in a legend immediately following the title to be understandable without reference to the text. Figure should have titles and explanatory legends that contain sufficient detail to make the figure easily understood. All images must have a minimum resolution of 300 dpi.
  • 7) Supplementary material:
    You have the option to submit supporting data, tables, figures and movies as supplementary material to be published online alongside the electronic version of your article. In order to ensure that your submitted material is directly usable, please provide the data in well-known and common file formats. When appropriate, supplementary material may be included in the manuscript file upon initial submission.