Biomedical Science Letters

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Fig. 1.

Adaptation and selection of HFD mice for examining the anti-obesity activities. Seven groups were prepared and used in this study. Total 56 adapted mice on HFD were selected based on the body weight at 7 days after initiation of HFD supply, and 2 mice in each group were removed based on the standard deviation of body weight at end of 84 days of administrations or mortalities; 6 mice per groups, total 42 mice were sacrificed. All test materials and two different reference drugs were directly diluted or dissolved in distilled water, and administered in a volume of 10 mL/kg, once a day for 84 days from 1 week after HFD supply. HFD, high-fat diet; HBV, herbal black vinegar.

Biomed Sci Letters 2018;24:380-9
© 2018 Biomed Sci Letters