Liver pathology scores of 8-week oral repeated dose MYE
group | Cell necrosis | Destruction of lobular structure | Fatty change | Ito cell | Lesions (maximum score) | Total |
---|---|---|---|---|---|---|
G1 | 0 | 0 | 0.2 | 0 | 0 | 0.2 |
G2 | 0 | 0.5 | 3.0 | 2.9 | 3.0 | 9.4 |
G3 | 0 | 0.1 | 0.7 | 1.2 | 1.4 | 3.4 |
G4 | 0 | 0.1 | 0.4 | 0.9 | 0.6 | 2.0 |
G5 | 0 | 0 | 0.2 | 0.3 | 0.3 | 0.8 |
G6 | 0 | 0 | 0.3 | 0.5 | 0.4 | 1.2 |