Biomedical Science Letters

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Fig. 2. Effect of FGE on the expression of (A) SOD, (B) CAT and (C) MT-1A genes in H2O2-induced HepG2 cells. HepG2 cells were treated with FGE (0.625, 1.25 and 2.5 μg/mL) for 24 h and then 400 μM H2O2 induced oxidative stress for a further 9 h. The mRNA expressions were analyzed by qRT-PCR. The cells were collected and (A) SOD, (B) CAT and (C) MT-1A mRNA level were estimated NC was treated with only the SFM (Serum Free Media). The present data were expressed mean ± SD. Different superscripts mean a significant difference among groups (P<0.05) based on one-way ANOVA and Duncan's multiple range test. FGE, ethanol extract of Filipendula glaberrima Nakai; NC, Negative control; Asc, Ascorbic acid.
Biomed Sci Letters 2022;28:25-33
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