Biomedical Science Letters

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Fig. 1. Genome-wide distribution of histone H3K27ac and H3K27me3. (A) Genome browser shows distribution of histone H3K27ac and H3K27me3 in K562 cells. Public K562 ChIP-seq data were obtained from GEO database. Red and pale blue shadows represent H3K27ac- and H3K27me3-enriched regions, respectively. (B) Distribution of H3K27ac and H3K27me3 was visualized using density heatmap at transcription start sites (TSSs) ±5 Kb. TSSs were sorted by H3K27ac or H3K27me3 levels at TSSs ±5 Kb. Density heatmap was expanded to TSSs ±20 Kb with same ordering.
Biomed Sci Letters 2022;28:109-19
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