Biomedical Science Letters

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Fig. 3. Peak calling in histone H3K27ac and H3K27me3 ChIP-seq data of control K562 cells. H3K27ac and H3K27me3 ChIP-seq were carried out in K562 control (Con) cells with two replicates (R1 and R2). (A) Scatter plots show correlation of public ChIP-seq data with Con R1 and R2 ChIP-seq data with Spearman correlation coefficients. (B) The correlation coefficients were also measured between H3K27ac and H3K27me3 ChIP-seq data and visualized by a heatmap. (C) Genome browser shows peaks identified by three analysis methods in green rectangles. (D) The S/B ratio of H3K27ac and H3K27me3 peaks was compared between three analysis methods with two replicates. Difference of the S/B ratio was indicated in multiples.
Biomed Sci Letters 2022;28:109-19
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