Fig. 5. PD-L1 protein silencing efficacy by immuno-DCD[siRNA] and cytotoxic effect by immuno-PCD[SAHA].
(A) A549 cells were incubated with PCD and immuno-PCD at the varied concentration of SAHA (5~15 μM) for 48 h. And then, cell viability was measured by WST assay. Error bars represent standard deviation of three independent experiments. *P<0.05 compared with PCD[SAHA] and Immuno-PCD[SAHA]. (B) A549 cells were incubated with PCD and immuno-PCD at the varied concentration of SAHA (5~15 μM) for 48 h. The cell viability was measured by WST assay. Error bars represent standard deviation of three independent experiments. A; ***P<0.001 compared with SAHA 10 μM group, **P<0.01 compared with DCD[siRNA] group. B; *P<0.05 compared with PCD[SAHA] and Immuno-PCD[SAHA].
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