Fig. 1. Heatmap of a Spaniard cohort study. A total of 346 (59% women) healthy Spaniards from southern Spain were included for the study. Subjects were divided by sex and age as young group (18~34.9 years), middle-aged group (35~54.9 years), and senior group (55~85 years). Average sKL concentrations in blood for the aged groups are displayed. Numbers indicate concentration of sKL (pg/mL). M & F indicates male and female. n means number of participants. Statistical significance is indicated using asterisks: *indicates significant (P<0.05), ***indicates highly significant (P<0.001).
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