Fig. 5. The flowchart of interpretation of modified carbapenem inactivation method (mCIM) and EDTA-modified carbapenem inactivation method (eCIM). Opening the black box of phenotypic carbapenemase detection. mCIM is used for detecting carbapenemase in Enterobacterales whereas eCIM is used together with mCIM to differentiate metallo-β-lactamse (Class B) from serine carbapenemase (Class A) [CLSI, 2018].
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