Fig. 2. Effect of Der p 38 and Der f 38 on basophil activation in allergic subjects.
Granulocytes were isolated from asthma [Der p 38+/ Der f 38+ (n = 3) and Der p 38-/Der f 38+ (n = 2)] (A) and allergic disease including allergic rhinitis and atopic dermatitis [Der p 38+/Der f 38+ (n = 5), Der p 38-/Der f 38+ (n = 1), and Der p 38+/Der f 38- (n = 4)] (B). The cells were stimulated with Der p 38 or Der f 38 (10 mg /mL). The CD203c expression of basophils was evaluated using flow cytometry. *P < 0.05 indicates a significant difference between the Der p 38 and Der f 38 stimulated groups.
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