Fig. 2. Assessing the effect of Vemurafenib on NK Cell Anti-Tumor Activity. (A, B) Evaluating the degranulation and cytokine release of NK cells when challenged with K562 and CEM tumor targets. This was done by staining for surface CD107a and intracellular IFN-γ. (C, D) NK cell cytotoxicity against tumors was quantified by measuring LDH activity. The results are derived from three separate experiments, each employing PBMCs from different donors, and are presented as the mean ± SEM. *, P < 0.05; **, P < 0.01.
© 2023 Biomed Sci Letters
