Fig. 3. Anticancer efficacy by aptamosome [SAHA] in LL/2 cells.
(A) LL/2 cells were treated with different formulations for 48 h. The cell viability is evaluated via MTT assay and measured at 570 nm. The cell viability is indicated as % compared to an untreated control group. (B and C) LL/2 cells were treated with different formulations for 48 h. Apoptosis assays were performed with the annexin-V-FITC/PI flow cytometry analysis to measure total apoptosis levels. Data are represented as the mean ± SD for triplicate experiments. A; ***P<0.001 compared with liposome [SAHA] and aptamosome [SAHA]. C; **P<0.01 compared with liposome [SAHA] and aptamosome [SAHA]. A and C; *P<0.05 compared with SAHA and aptamosome [SAHA].
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