Association analysis between the significant four SNPs in the
| Traits | rs474279 | rs657152 | rs641943 | rs641959 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Effect size (β ± s.e) | Effect size (β ± s.e) | Effect size (β ± s.e) | Effect size (β ± s.e) | ||||||||
| Blood glucose | |||||||||||
| Glu0 | -1.37±0.41 | 0.0007 | 1.32±0.33 | 7.27E-05 | -1.25±0.40 | 0.0021 | -1.18±0.41 | 0.0040 | |||
| Glu60 | -2.94±1.01 | 0.0036 | 1.91±0.82 | 0.0204 | -2.59±1.00 | 0.0098 | -2.31±1.01 | 0.0225 | |||
| Glu120 | -2.44±0.96 | 0.0109 | 1.53±0.79 | 0.0510 | -2.04±0.95 | 0.0321 | -2.13±0.96 | 0.0271 | |||
| HbA1C | -0.03±0.02 | 0.0525 | 0.04±0.01 | 0.0068 | -0.02±0.02 | 0.1500 | -0.03±0.02 | 0.1226 | |||
| Blood insulin | |||||||||||
| Ins0 | -0.08±0.09 | 0.3529 | -0.03±0.07 | 0.6780 | -0.06±0.09 | 0.5100 | -0.08±0.09 | 0.3953 | |||
| Ins60 | 0.26±0.60 | 0.6587 | -1.23±0.49 | 0.0120 | 0.31±0.59 | 0.6057 | 0.41±0.53 | 0.4957 | |||
| Ins120 | -0.14±0.53 | 0.7973 | -0.94±0.43 | 0.0299 | 0.09±0.53 | 0.8694 | 0.00±0.53 | 0.9968 | |||
Abbreviations: Glu0, fasting plasma glucose; Glu60, plasma glucose at 60 min; Glu120, plasma glucose at 120 min; HbA1c, glycosylated hemoglobin A1c; Ins0, fasting plasma insulin; Ins60, plasma insulin at 60 min; Ins120, plasma insulin at 120 min; T2DM, type 2 diabetes mellitus
*Statistically significant values (
