Biomedical Science Letters

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Table. 3.

Non-susceptible rates for antifungal agents in Candida species from blood culture during 2016 to 2023 year

Phase MO N Frequency of non-susceptibility for antifungal agents non-susceptible number/test number (non-susceptible %)

AMP FCT FLC VRC CAS MCF
2016-2019 C. alb 59 3/59 (5.08) 2/59 (5.13) 2/59 (3.39) 1/59 (1.69) 0 0
C. gla 29 0 0 4/29 (14.81) 1/29 (3.45) 2/29 (6.90) 0
C. par 19 1/19 (5.26) 0 0 0 1/19 (5.26) 0
C. tro 22 0 0 0 0 0 0
Total 129 4/129 (3.10) 2/118 (1.69) 6/129 (4.65) 2/129 (1.55) 3/129 (2.33) 0

2020-2023 C. alb 100 3/99 (3.03) 3/100 (3.00) 1/100 (1.00) 12/99 (12.12) 2/100 (2.00) 2/100 (2.00)
C. gla 32 0 0 NT 0 13/32 (40.63) 0
C. par 33 1/33 (3.03) 0 0 0 0 0
C. tro 39 0 0 2/39 (5.13) 1/39 (2.56) 0 0
Total 204 4/204 (1.96) 3/204 (1.47) 3/172 (1.74) 13/204 (6.37) 15/204 (7.35) 2/204 (0.98)

2016-2023 C. alb 159 6/158 (3.80) 5/139 (3.60) 3/159 (1.89) 13/158 (8.23) 2/159 (2.52) 2/159 (1.26)
C. gla 61 0 0 4/27 (14.81) 1/61 (1.64) 15/61 (24.59) 0
C. par 52 2/52 (3.85) 0 0 0 1/52 (1.92) 0
C. tro 51 0 0 2/51 (3.92) 1/51 (1.96) 0 0
Total 323 8/322 (2.48) 5/292 (1.71) 9/291 (3.09) 15/322 (4.66) 18/323 (5.57) 2/323 (0.62)

Abbreviations: N, number; MO, microorganism; AMP, amphotericin B; FCT, flucytosine; FLC, fluconazole; VRC, voriconazole; CAS, caspofungin; MCF, micafungin; C. alb; C. albicans; C. gla, C. glabrata; C. par, C. parapsilosis; C. tro, C. tropicalis; NT, not tested

Biomed Sci Letters 2024;30:73-80 https://doi.org/10.15616/BSL.2024.30.2.73
© 2024 Biomed Sci Letters