Biomedical Science Letters

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Fig. 2. Effects of Angelica gigas Nakai (AG) on cell viability and histamine release in activated human mast cells-1. (A) Cells (3 × 105 cells/well) were treated with various concentration of AG (0.01, 0.1, and 1 mg/mL) for 24 hours and cell viability was measured using the MTS assay. (B) Cells were treated with various concentration of AG (0.01, 0.1, and 1 mg/mL) for 1 hour before activation with PMA plus 1 mg/mL of calcium Ionophore A23187 (PMACI) for 2 hours. Dexamethasone (Dex, 100 nM) was used as positive control. The histamine concentration was assessed using histamine assay kits. Results are shown the mean ± standard deviation of experiments. #P < 0.05, significantly different from control (vehicle); *P < 0.05, significantly different from PMACI-treatments.
Biomed Sci Letters 2024;30:238-47 https://doi.org/10.15616/BSL.2024.30.4.238
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