Biomedical Science Letters

eISSN 2288-7415

Download original image
Fig. 2. Genotype-based mRNA expression in Adipose- Visceral (Omentum) tissue using data from the GTEx Portal for SNP (rs3792234) of STON1 (P-value = 6.4 × 10-11, NES = –0.20. Significant associations between genotypes and STON1 expression levels in the GTEx portal were detected based on linear regression models and P-value thresholds determined by the GTEx portal’s web-based expression quantitation trait loci calculator. The allele effects on STON1 gene expression levels are shown by box plots within violin plots. G and T represent the major and minor allele types, respectively. The white line in the box plot (black) represents the median value of gene expression in each genotype. In the case of having a minor allele (G > T), it shows that the gene expression level is reduced. P-values are calculated using a linear regression model. NES means the slope of the linear regression model. NES, normalized effect size.
Biomed Sci Letters 2024;30:298-305 https://doi.org/10.15616/BSL.2024.30.4.298
© 2024 Biomed Sci Letters