Search for


TEXT SIZE

search for




CrossRef (0)
Neuroprotective Effect of Natural Product in Alzheimer’s Disease
Biomed Sci Letters 2024;30:189-198
Published online December 31, 2024;  https://doi.org/10.15616/BSL.2024.30.4.189
© 2024 The Korean Society For Biomedical Laboratory Sciences.

Jin-Seok Kim* and Hyun-Jeong Cho†,**

Department of Biomedical Laboratory Science, College of Medical Science, Konyang University, Daejeon 35365, Korea
Correspondence to: †Hyun-Jeong Cho
Department of Biomedical Laboratory Science, College of Medical Science, Konyang University, 158 Gwanjeodong-ro, Seo-gu, Daejeon 35365, Korea
Tel: +82-42-600-8433, Fax: +82-42-600-8408
E-mail: hjcho@konyang.ac.kr
ORCID: https://orcid.org/0000-0003-2331-1306

*Graduate student, **Professor.
Received August 22, 2024; Revised November 28, 2024; Accepted November 28, 2024.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Alzheimer’s disease, one of the neurodegenerative diseases, affects millions of people. People with Alzheimer's disease have difficulty with daily life due to cognitive and physical impairment. The cause of Alzheimer's disease is unclear, but several treatments are being used to target the main pathological factors. The drugs currently being used have limitations in that they can’t completely treat the disease and have side effects. Therefore, research is being conducted on natural products such as medicinal plants, fruits, and marine organisms as potential therapeutic strategies for Alzheimer’s disease. Natural products have been used in various commercial sectors such as food and cosmetics since the past, and they have been used for various diseases due to their inflammation-improving and anti-cancer effects. Researchers are studying natural products as therapeutics for neurodegenerative diseases because they may have neuroprotective roles, such as alleviating neuroinflammation and modulating systemic immune responses. Moreover, they have been shown to play a neuroprotective role, including preventing amyloid beta formation and inhibiting hyperphosphorylation of tau proteins. Natural products, unlike conventional drugs, have fewer side effects and are economical, indicating their potential as new treatment strategies for Alzheimer’s disease.
Keywords : Alzheimer’s disease, Biological products, Amyloid beta-peptides, Neuroinflammatory diseases, Tau proteins, Oxidative stress, Mitochondrial diseases