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The Biomed. Sci. Lett. encourages the submission of manuscripts describing primarily original investigations in the broad fields of biomedical sciences, molecular and cellular biology, cancer biology, neuroscience, biochemistry, genetics, immunology, microbiology, pharmacology and physiology. Reports of purely laboratory or animal investigations should have a clear bearing on the problems of animal and human diseases. The journal will consider manuscripts that are primarily methodologic if the method is novel, if its development poses or answers important biologic questions, or if its description includes data applying it to a study of potential interest to our readership.